Probiotic yogurt may ease common cold symptoms in healthy adults: RCT


Twelve weeks of consuming a yogurt formulated with Lactobacillus paragasseri​ SBT2055 (LG2055) led to fewer cold symptoms, such as runny nose, plugged nose, sneezing, sore throat, hoarseness, cough, headache, feeling tired, and fever, compared to the placebo group.

The study, which included 200 people, also found that the probiotic yogurt group had significantly greater changes in salivary sIgA levels. Secretory immunoglobulin A (sIgA) is found on bodily surfaces and in secretory fluids like mucus and is known to be the first line of defense in protecting against infection.

“The findings suggest that the incidence rates of the symptoms associated with common cold were lesser in the LG2055 group, and LG2055 might suppress the deterioration of physical conditions by maintaining and improving the host’s immune system,” ​wrote the researchers in Frontiers in Nutrition​.

Study details

The 12 week randomized, double-blind, placebo-controlled, parallel-group comparative study included 200 healthy Japanese adults aged between 20 and 64 provided with a one bottle of drinkable yogurt per day with or without the LG2055 probiotic containing a minimum of one billion CFUs per 100 grams.

Analysis of data from 193 people showed that the cumulative days of cold symptoms were significantly lower for people receiving the probiotic yogurt. This result indicated that “the incidence rates of common cold symptoms were lower in the LG2055 group”,​ said the researchers.

In addition, there were greater changes in salivary secretory IgA levels in the probiotic group, although statistically these were not significant between the groups.


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